Murray Valley Highway closed after fatal crash at Yalca

According to police, it is understood a truck and car collided before the truck veered off the road and crashed into a tree.

The driver of the truck died at the scene.

A man in his 80s who was driving the car was taken to Goulburn Valley Health in a stable condition.

A female passenger also in her 80s was flown to the Royal Melbourne Hospital by air ambulance helicopter with serious injuries in a stable condition.

The Murray Valley Hwy is closed to traffic in both directions between the Goulburn Valley Hwy and Tyacks Rd.

Motorists are advised to use Katamatite-Nathalia Rd instead.

The section of highway is expected to be closed for hours while investigations are underway.

Anyone who witnessed the collision, has dashcam or CCTV footage or information is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au